Reductil (Sibutramine) is a serotonin and noradrenaline reuptake inhibitor, which means that it works by affecting brain chemistry.
Provigil-treated patients also experienced a decrease from baseline in the frequency and duration of attention lapses during nighttime testing,
Provigil has been thought to produce its wake-promoting effects independent of dopaminergic actions.
Provigil may be a potentially effective treatment for primary biliary cirrhosis PBC-related fatigue.